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KMID : 0358319740150030195
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Korean Journal of Urology
1974 Volume.15 No. 3 p.195 ~ p.199
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Clinical Effect of Spectinomycin on Acute Gonorrheal Urethritis
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조대행/Cho DH
정성영/윤문수/어영선/임수길/Chung SY/Yoon MS/Uh YS/Lim SK
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Abstract
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Forty five gonococcal patients were treated with spectinomycin hydrochloride at the Department of Urology, St. Mary`s Hospital from August 1. 1972 to December 32. 1972. All patients were male and confirmed as acute gonorrheal urethritis by gram stained smear or culture. The cure ability in this series was very satisfactory The results were as follows; 1. Gram negative ;intracellular diplococci was controlled in 29 patients (96.7%) among 3O patients with pure gonococcal infection with a single injection of spectinomycin hydrochloride. 2. Gram negative intracellular diplococci was controlled in 14 patients (93.3%) among 15 patient with mixed infection with a single injection of spectinomycin hydrochloride. 3. Only two in all patients were controlled in gram negative intracellular diplococci with repeat injection. 4. 4 patients (13.3%) of the pure gonoccoccal patients with a single injection were converted to non-specific urethritis, which were treated with combination of other antibiotics. 5. 5 patients (33.3%) of the mixed infected patients with a single injection were converted to nonspecific urethritis, which were treated with combination of other antibiotics. 6. No side effect was noted in all patients.
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